Jessica fink raleigh nc9/12/2023 ![]() PepsiCo's product portfolio includes a wide range More than $86 billion in net revenue in 2022, driven by a complementary beverage and convenient foods portfolio that includes Lay's, Doritos, Cheetos, Gatorade, Pepsi-Cola, Mountain Dew, Quaker, and SodaStream. PepsiCo products are enjoyed by consumers more than one billion times a day in more than 200 countries and territories around the world. Ramon Laguarta is the Chairman of the Board of Directors and Chief Executive Officer of PepsiCo. Government & Policy Government & Policy.PepsiCo Health and Nutrition Sciences PepsiCo Health and Nutrition Sciences. ![]() PepsiCo Product Facts PepsiCo Product Facts.PepsiCo Beverage Facts PepsiCo Beverage Facts.PepsiCo Smart Label PepsiCo Smart Label.Nutrition Information Nutrition Information.PepsiCo Jobs Instagram PepsiCo Jobs Instagram.Restaurants & Businesses Restaurants & Businesses.Customers & Shoppers Customers & Shoppers.et al.Global gene expression profiling in Escherichia coli K12: effects of oxygen availability and ArcA. Salmon KA, Hung SP, Steffen NR, Krupp R, Baldi P, Hatfield GW. Macrophage-dependent induction of the Salmonella pathogenicity island 2 type III secretion system and its role in intracellular survival. doi: 10.1046/j.Ĭirillo DM, Valdivia RH, Monack DM, Falkow S. Molecular basis of Salmonella induced enteritis. Salmonella interactions with host cells: type III secretion at work. et al.Identification of host-specific colonization factors of Salmonella enterica serovar Typhimurium. Morgan E, Campbell JD, Rowe SC, Bispham J, Stevens MP, Bowen AJ. Furthermore, ArcA and Fnr share in the regulation of 120 S. Typhimurium, ArcA serves as a transcriptional regulator coordinating cellular metabolism, flagella biosynthesis, and motility. We have identified the ArcA regulon in anaerobically grown S. Additionally, we identified a set of 120 genes whose regulation was shared with the anaerobic redox regulator, Fnr. In agreement with our microarray data, the arcA mutant was non-motile, lacked flagella, and was as virulent in mice as the WT. Salmonella-specific genes/operons regulated by ArcA included those required for propanediol utilization, flagellar genes (mcpAC, cheV), Gifsy-1 prophage genes, and three SPI-3 genes (mgtBC, slsA, STM3784). Typhimurium included those coding for ethanolamine utilization, lactate transport and metabolism, and succinate dehydrogenases. However, genes/operons present in both organisms, but regulated differently by ArcA in S. Thus, genes/operons involved in core metabolic pathways (e.g., succinyl-CoA, fatty acid degradation, cytochrome oxidase complexes, flagellar biosynthesis, motility, and chemotaxis) were regulated similarly in the two organisms. Typhimurium is similar, but distinct from that in E. We found that ArcA directly or indirectly regulates 392 genes (8.5% of the genome) of these, 138 genes are poorly characterized. We compared the transcriptional profiles of the virulent wild-type (WT) strain (ATCC 14028s) and its isogenic arcA mutant grown under anaerobic conditions. coli is well characterized however, little is known about its role in anaerobically grown S. In Escherichia coli, ArcA (Aerobic Respiratory Control) helps the cells to sense and respond to the presence of dioxygen. Typhimurium) is a Gram-negative pathogen that must successfully adapt to the broad fluctuations in the concentration of dissolved dioxygen encountered in the host. Salmonella enterica serovar Typhimurium (S.
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